LINC02466

Across TCGA pan-cancer cohorts, LINC02466 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02466’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02466 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02466 is over-expressed in tumor.

HNSC, LUSC, and KIRC are the cancer types where LINC02466 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02466 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.389	<.001	9	view →
LUSC	All	All	+0.427	<.001	6	view →
KIRC	All	All	+0.007	.005	6	view →
LIHC	All	All	+0.120	<.001	5	view →
LUAD	All	All	+0.114	.001	4	view →
UCEC	All	IV	+0.090	.012	4	view →
BRCA	Female	All	+0.051	.010	4	view →
BLCA	All	All	+0.332	.015	3	view →
COAD	All	All	+0.033	.029	2	view →
STAD	All	All	+0.067	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02466–HNSC

Open the HNSC breakdown →