LINC02457

Across TCGA pan-cancer cohorts, LINC02457 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LINC02457 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher LINC02457 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC02457 expression acts as an unfavorable survival marker, although some lineages such as CESC and ESCA show a favorable association.

CESC, UVM, and HNSC are the cancer types where LINC02457 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.829	0.700	.014	82	view →
UVM	OS	Tertile	All	0.104	0.834	<.001	63	view →
HNSC	OS	Median	III,IV	0.366	0.682	<.001	28	view →
ESCA	OS	Median	II,III,IV	0.792	0.619	.009	21	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	18	view →
COAD	OS	Tertile	IV	0.089	0.676	<.001	18	view →
UCEC	DFS	Tertile	All	0.826	0.905	.013	18	view →
SKCM	DFS	Tertile	IV	0.066	0.511	.047	9	view →
ACC	DFS	Tertile	All	0.204	0.658	.008	9	view →
KIRP	OS	Quartile	III,IV	0.846	0.341	.018	8	view →
DLBC	OS	Quartile	II,III,IV	0.725	1.000	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LINC02457–CESC (DFS)

Open the CESC breakdown →