LINC02375

Across TCGA pan-cancer cohorts, LINC02375 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated LINC02375 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher LINC02375 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02375 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

DLBC, TGCT, and KIRC are the cancer types where LINC02375 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	36	view →
KIRC	DFS	Tertile	IV	0.275	0.669	.004	30	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	18	view →
UCS	OS	Tertile	All	0.185	0.686	.034	18	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	12	view →
GBM	DFS	Tertile	All	0.125	0.344	<.001	9	view →
LIHC	DFS	Tertile	All	0.156	0.533	.013	9	view →
PCPG	DFS	Tertile	All	0.535	0.935	.028	9	view →
HNSC	DFS	Tertile	II,III,IV	1.000	0.315	.045	3	view →
KICH	DFS	Quartile	III,IV	0.298	0.827	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

LINC02375–DLBC (OS)

Open the DLBC breakdown →