LINC02349

Across TCGA pan-cancer cohorts, LINC02349 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated LINC02349 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC02349 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC02349 expression acts as an unfavorable survival marker, although some lineages such as OV and THCA show a favorable association.

HNSC, OV, and UCEC are the cancer types where LINC02349 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.199	0.602	<.001	120	view →
OV	OS	Tertile	All	0.529	0.287	<.001	108	view →
UCEC	DFS	Tertile	III,IV	0.651	0.815	.008	72	view →
THCA	DFS	Tertile	All	0.940	0.774	.001	59	view →
LGG	OS	Median	All	0.371	0.532	<.001	53	view →
READ	OS	Tertile	All	0.284	0.842	.001	27	view →
STAD	DFS	Tertile	All	0.517	0.649	.037	9	view →
LUSC	OS	Tertile	All	0.325	0.661	.047	9	view →
PCPG	DFS	Tertile	All	0.097	0.817	<.001	9	view →
LUAD	DFS	Tertile	All	0.858	0.331	.035	9	view →
SARC	DFS	Tertile	All	0.817	0.538	.007	9	view →
PRAD	OS	Tertile	All	0.932	0.990	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

LINC02349–HNSC (DFS)

Open the HNSC breakdown →