LINC02274

Across TCGA patient cohorts, LINC02274 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,027 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC02274-associated GO terms across cancer lineages are Positive regulation of apoptotic signaling pathway, Cellular response to oxidative stress, and Non-canonical NF-kappaB signal transduction. Each is linked with LINC02274 in more than 15 cancer types. Because this analysis shows association rather than direction, both LINC02274-to-partner and partner-to-LINC02274 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of apoptotic signaling pathway grouped by LINC02274-low versus LINC02274-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02274→partner) and Y-score (partner→LINC02274) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of apoptotic signaling pathway →	+0.049	+0.200	<.001	<.001	3	16
STAD	Cellular response to oxidative stress →	+0.047	+0.201	<.001	<.001	3	15
ESCA	Non-canonical NF-kappaB signal transduction →	+0.059	+0.203	<.001	<.001	2	16
ESCA	Integrated stress response signaling →	+0.082	+0.286	<.001	<.001	3	14
STAD	Maintenance of location in cell →	+0.042	+0.271	<.001	<.001	3	14
ESCA	Establishment of endothelial barrier →	+0.060	+0.287	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,027 associations by consensus.

Positive regulation of apoptotic signaling pathway by LINC02274 expression — STAD

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