LINC02274

Across TCGA pan-cancer cohorts, LINC02274 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC02274 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher LINC02274 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02274 expression acts as an unfavorable survival marker, although some lineages such as KIRC and CHOL show a favorable association.

CESC, BRCA, and UVM are the cancer types where LINC02274 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.455	0.679	.004	52	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	45	view →
UVM	OS	Tertile	III,IV	0.199	0.836	<.001	35	view →
KIRC	DFS	Tertile	All	0.831	0.693	.009	33	view →
THCA	DFS	Tertile	II,III,IV	0.573	0.886	.001	33	view →
CHOL	DFS	Tertile	All	0.748	0.340	.010	28	view →
BLCA	DFS	Median	All	0.633	0.412	.016	22	view →
GBM	OS	Tertile	All	0.324	0.506	.002	21	view →
ACC	OS	Quartile	III,IV	0.888	0.330	.011	18	view →
MESO	OS	Tertile	All	0.662	0.222	.017	15	view →
ESCA	DFS	Tertile	IV	0.231	0.704	.024	13	view →
LUAD	DFS	Median	All	0.838	0.700	.004	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC02274–CESC (OS)

Open the CESC breakdown →