LINC02242

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC02242 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC02242’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02242 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02242 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, THCA, and LUAD are the cancer types where LINC02242 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02242 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllIII,IV−0.462<.0016view →
THCAMaleAll−0.342<.0016view →
LUADAllII,III,IV−0.145.0106view →
KIRCMaleAll+0.094.0056view →
LIHCAllAll+0.094.0074view →
BLCAAllAll+0.286.0482view →
PRADAllAll−0.263<.0012view →
COADAllIV+0.194.0392view →
UCECAllAll−0.137.0172view →
KICHAllAll−0.089.0262view →
STADMaleII,III,IV−0.125.0381view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC02242–BRCA

Tumor-vs-normal expression box plot for LINC02242 RNA in BRCA.

Open the BRCA breakdown →

Exploration