LINC02225

Across TCGA patient cohorts, LINC02225 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,000 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LINC02225-associated proteins across cancer lineages are SHANK3_S1522, NIP7, and DYNC1LI2_S194. Each is linked with LINC02225 in more than 2 cancer types. Because this analysis shows association rather than direction, both LINC02225-to-partner and partner-to-LINC02225 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC02225 versus SHANK3_S1522 in CCRCC, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02225→partner) and Y-score (partner→LINC02225) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SHANK3_S1522 →	-0.701	-0.405	.007	.002	3	3
LSCC	NIP7 →	+0.416	+0.112	<.001	.002	3	3
LUAD	DYNC1LI2_S194 →	+0.299	+0.024	.001	.002	3	3
LUAD	EIF3J_T109 →	+0.485	+0.026	<.001	.001	3	3
GBM	THRAP3_S264 →	-0.376	-0.040	<.001	<.001	3	2
CCRCC	NDUFAF8 →	+0.650	+0.355	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,000 associations by consensus.

LINC02225 vs SHANK3_S1522 — CCRCC

Explore this scatter interactively →