LINC02225

Across TCGA pan-cancer cohorts, LINC02225 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LINC02225 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC02225 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02225 expression acts as an unfavorable survival marker, although some lineages such as GBM and LGG show a favorable association.

KIRC, CHOL, and KICH are the cancer types where LINC02225 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.548	0.701	<.001	62	view →
CHOL	OS	Tertile	II,III,IV	0.193	0.896	.002	60	view →
KICH	OS	Tertile	II,III,IV	0.274	0.867	<.001	54	view →
BRCA	DFS	Quartile	All	0.841	0.913	<.001	48	view →
MESO	OS	Tertile	All	0.356	0.597	<.001	39	view →
GBM	OS	Tertile	All	0.427	0.228	.012	24	view →
OV	OS	Median	III,IV	0.788	0.879	.003	20	view →
BLCA	DFS	Tertile	IV	0.194	0.512	<.001	19	view →
COAD	DFS	Tertile	IV	0.246	0.526	.021	18	view →
PAAD	OS	Tertile	II,III,IV	0.403	0.624	.001	17	view →
UVM	OS	Tertile	III,IV	0.223	0.709	.045	9	view →
LGG	OS	Tertile	All	0.614	0.396	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LINC02225–KIRC (OS)

Open the KIRC breakdown →