LINC02188

Across TCGA pan-cancer cohorts, LINC02188 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02188’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02188 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02188 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

KIRC, KIRP, and COAD are the cancer types where LINC02188 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02188 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+3.019	<.001	12	view →
KIRP	Male	II,III,IV	+1.864	<.001	7	view →
COAD	All	II,III,IV	+0.142	.002	7	view →
BRCA	All	III,IV	−2.482	<.001	6	view →
KICH	Female	II,III,IV	−0.750	<.001	5	view →
THCA	All	All	+0.081	.003	4	view →
PAAD	All	All	+1.989	.019	2	view →
LUAD	All	All	+0.447	.009	2	view →
LUSC	Male	All	+0.349	.002	2	view →
LIHC	All	All	+0.114	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02188–KIRC

Open the KIRC breakdown →