LINC02181

Across TCGA pan-cancer cohorts, LINC02181 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02181’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC02181 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02181 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and KIRC are the cancer types where LINC02181 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02181 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	−0.057	<.001	7	view →
KICH	All	All	−0.149	<.001	6	view →
KIRC	All	II,III,IV	−0.053	.003	4	view →
BRCA	All	All	+0.053	.047	2	view →
COAD	Female	III,IV	+0.034	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC02181–KIRP

Open the KIRP breakdown →