LINC02157

Across TCGA pan-cancer cohorts, LINC02157 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC02157’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC02157 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02157 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, BRCA, and LUSC are the cancer types where LINC02157 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02157 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.617	<.001	9	view →
BRCA	All	III,IV	−0.262	<.001	8	view →
LUSC	All	All	−0.229	<.001	5	view →
UCEC	All	All	−0.470	<.001	4	view →
LUAD	Female	II,III,IV	−0.281	.002	3	view →
KIRP	Female	II,III,IV	−0.526	.024	2	view →
ESCA	All	All	−0.638	.029	1	view →
CHOL	All	All	+0.354	.045	1	view →
COAD	Male	III,IV	−0.169	.048	1	view →
LIHC	All	II,III,IV	+0.051	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC02157–KICH

Open the KICH breakdown →