long intergenic non-protein coding RNA 2157Genealiases: []
Q-omics provides the consensus-scored LINC02157 profile across patient tissues and cancer cell-line models. LINC02157 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in LGG. Among the 18 cancer types available for tumor–normal comparison, LINC02157 is differentially expressed in 10, with the highest sampling consensus in KICH. Additionally, LINC02157 RNA expression shows 19,085 significant protein co-abundance associations, with the highest sampling consensus in PDAC. Together, these results highlight LGG, KICH, and PDAC as cancer lineages where LINC02157 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02157 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02157 survival associations across molecular data types. LINC02157 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02157 RNA expression–survival associations across cancer types. High LINC02157 expression shows unfavorable associations in LGG, ACC, MESO and CESC, but favorable associations in ESCA and BRCA. The LGG Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LGG as the clearest survival context for LINC02157 RNA expression.
This table summarizes LINC02157 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02157. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02157 shows lower tumor expression in KICH, BRCA, LUSC, UCEC, LUAD and KIRP. The KICH box plot shows higher LINC02157 RNA expression in normal versus tumor tissue (log2 FC = −0.617, t-test p < 0.001).
This table shows molecular features associated with LINC02157 in patient tissues and cancer cell lines. In patient samples, LINC02157 shows the broadest associations at the RNA and protein expression levels, with PDAC recurring as the lineage with the largest associated feature set.
