Across TCGA pan-cancer cohorts, LINC02151 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02151’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where LINC02151 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02151 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
STAD and LUAD are the cancer types where LINC02151 tumor–normal differential expression is most reproducible.