Across TCGA pan-cancer cohorts, LINC02060 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02060’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02060 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02060 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.
KIRC, THCA, and ESCA are the cancer types where LINC02060 tumor–normal differential expression is most reproducible.