Across TCGA pan-cancer cohorts, LINC01994 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01994’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01994 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01994 is over-expressed in tumor.
LUSC, KIRC, and LUAD are the cancer types where LINC01994 tumor–normal differential expression is most reproducible.