LINC01991

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01991 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC01991 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher LINC01991 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01991 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

MESO, KIRP, and KIRC are the cancer types where LINC01991 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSTertileIII,IV0.1730.443.00272view →
KIRPDFSTertileIII,IV0.4020.749.00466view →
KIRCDFSTertileAll0.5820.825<.00154view →
BLCADFSMedianIV0.6630.312.00547view →
SKCMOSQuartileAll0.8720.756<.00147view →
PAADDFSTertileII,III,IV0.5580.399.01244view →
DLBCDFSTertileAll1.0000.502<.00138view →
READOSTertileIV0.1110.893<.00127view →
CHOLDFSTertileAll0.8920.256.00121view →
CESCDFSTertileIII,IV0.8840.664.04212view →
THCADFSQuartileIII,IV0.8050.959.00611view →
LIHCOSMedianAll0.3330.565.0119view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration