Across TCGA pan-cancer cohorts, LINC01991 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01991’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01991 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01991 is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.

KIRC, COAD, and KICH are the cancer types where LINC01991 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01991 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.386	<.001	9	view →
COAD	Female	All	−0.070	.010	5	view →
KICH	All	All	−0.655	.001	4	view →
LUAD	All	II,III,IV	+0.061	.012	3	view →
THCA	All	All	−0.185	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: LINC01991 RNA expression & survival · all LINC01991 data types