LINC01974

Across TCGA pan-cancer cohorts, LINC01974 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated LINC01974 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher LINC01974 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01974 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PAAD show a favorable association.

ESCA, LIHC, and LUSC are the cancer types where LINC01974 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
LIHC	DFS	Tertile	All	0.165	0.560	.003	36	view →
LUSC	DFS	Tertile	III,IV	0.079	0.751	.024	27	view →
LUAD	DFS	Tertile	All	0.774	0.329	.030	24	view →
UVM	OS	Tertile	III,IV	0.220	0.811	.021	18	view →
PAAD	DFS	Tertile	All	0.696	0.254	.018	9	view →
PCPG	DFS	Tertile	All	0.786	0.937	.030	9	view →
BRCA	OS	Tertile	III,IV	1.000	0.893	.046	6	view →
PRAD	OS	Tertile	All	0.932	0.992	.007	6	view →
TGCT	DFS	Quartile	All	0.566	0.722	.045	4	view →
HNSC	DFS	Tertile	IV	0.458	0.679	.046	3	view →
LGG	DFS	Quartile	All	0.274	0.393	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

LINC01974–ESCA (OS)

Open the ESCA breakdown →