LINC01945

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01945 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01945’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01945 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01945 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and STAD are the cancer types where LINC01945 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01945 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADAllII,III,IV−0.212<.0019view →
LUSCAllII,III,IV−0.245<.0017view →
STADAllAll−0.228.0241view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC01945–LUAD

Tumor-vs-normal expression box plot for LINC01945 RNA in LUAD.

Open the LUAD breakdown →

Exploration