Across TCGA pan-cancer cohorts, LINC01890 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01890’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC01890 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01890 is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.
BRCA, KIRC, and LUAD are the cancer types where LINC01890 tumor–normal differential expression is most reproducible.