LINC01888

Across TCGA pan-cancer cohorts, LINC01888 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC01888’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01888 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01888 is over-expressed in tumor, although a few such as LUAD and BRCA show the opposite, repressed pattern.

KIRC, LUAD, and BRCA are the cancer types where LINC01888 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01888 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.086	<.001	11	view →
LUAD	All	II,III,IV	−0.256	.001	7	view →
BRCA	All	III,IV	−0.273	<.001	6	view →
LUSC	All	All	−0.162	<.001	6	view →
HNSC	Male	III,IV	+0.058	.020	6	view →
KICH	Female	III,IV	−0.130	.002	2	view →
BLCA	Female	All	−0.063	.022	2	view →
KIRP	All	All	+0.061	.005	2	view →
CHOL	All	All	+0.073	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LINC01888–KIRC

Open the KIRC breakdown →