LINC01869

Across TCGA patient cohorts, LINC01869 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,051 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible LINC01869-associated GO terms across cancer lineages are Positive regulation of sphingolipid biosynthetic process, Regulation of cytochrome-c oxidase activity, and Negative regulation of mRNA processing. Each is linked with LINC01869 in more than 20 cancer types. Because this analysis shows association rather than direction, both LINC01869-to-partner and partner-to-LINC01869 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of sphingolipid biosynthetic process grouped by LINC01869-low versus LINC01869-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01869→partner) and Y-score (partner→LINC01869) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of sphingolipid biosynthetic process →	+0.047	+0.368	<.001	<.001	3	21
MESO	Regulation of cytochrome-c oxidase activity →	+0.036	+0.327	<.001	.003	3	20
STAD	Negative regulation of mRNA processing →	+0.062	+0.231	<.001	<.001	3	18
READ	tRNA thio-modification →	+0.049	+0.280	.001	.001	2	18
STAD	Nucleolar large rRNA transcription by RNA polymerase I →	+0.066	+0.274	<.001	<.001	3	17
STAD	Regulation of protein folding →	+0.058	+0.321	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,051 associations by consensus.

Positive regulation of sphingolipid biosynthetic process by LINC01869 expression — STAD

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