LINC01869

Across TCGA pan-cancer cohorts, LINC01869 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC01869’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01869 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01869 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, KICH, and COAD are the cancer types where LINC01869 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01869 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.508	<.001	11	view →
KICH	Female	All	+0.858	<.001	9	view →
COAD	All	All	+0.287	<.001	6	view →
LUSC	All	All	+0.446	<.001	5	view →
LIHC	All	All	+0.129	<.001	5	view →
THCA	All	All	−0.324	<.001	4	view →
BRCA	All	All	+0.114	.017	4	view →
BLCA	All	All	+0.296	.010	3	view →
READ	Male	All	+0.166	.008	3	view →
PRAD	All	All	+0.519	<.001	2	view →
ESCA	All	II,III,IV	+0.339	.028	2	view →
STAD	All	All	+0.192	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC01869–HNSC

Open the HNSC breakdown →