LINC01812

Across TCGA patient cohorts, LINC01812 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,932 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC01812-associated GO terms across cancer lineages are Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway, Response to transforming growth factor beta, and Regulation of DNA damage response, signal transduction by p53 class mediator. Each is linked with LINC01812 in more than 11 cancer types. Because this analysis shows association rather than direction, both LINC01812-to-partner and partner-to-LINC01812 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway grouped by LINC01812-low versus LINC01812-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01812→partner) and Y-score (partner→LINC01812) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway →	+0.041	+0.122	<.001	<.001	3	12
STAD	Response to transforming growth factor beta →	+0.071	+0.219	<.001	<.001	3	12
STAD	Regulation of DNA damage response, signal transduction by p53 class mediator →	+0.051	+0.106	<.001	<.001	3	11
STAD	Fibroblast proliferation →	+0.048	+0.104	<.001	<.001	3	11
ESCA	Muscle cell migration →	+0.051	+0.267	<.001	.002	2	12
STAD	Stem cell division →	+0.037	+0.131	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,932 associations by consensus.

Positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway by LINC01812 expression — STAD

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