LINC01749

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01749 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC01749 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher LINC01749 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01749 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

ACC, LIHC, and HNSC are the cancer types where LINC01749 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSMedianAll0.3900.736<.001104view →
LIHCDFSTertileAll0.2640.458<.00172view →
HNSCDFSQuartileAll0.7850.657.00271view →
SKCMDFSTertileII,III,IV0.7570.660.00627view →
THYMOSMedianII,III,IV1.0000.885.00819view →
KICHOSTertileIII,IV0.1780.847<.00118view →
THCADFSTertileAll0.8320.907.02418view →
ESCAOSTertileAll0.6350.383.01315view →
STADDFSTertileIV0.7960.252.03812view →
MESOOSMedianIV0.8630.397.00710view →
UVMDFSTertileIII,IV0.1290.673.0179view →
READOSMedianII,III,IV0.8160.978.0247view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LINC01749–ACC (OS)

Kaplan–Meier survival curve for LINC01749 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration