LINC01749

Across TCGA pan-cancer cohorts, LINC01749 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC01749’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LINC01749 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01749 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

COAD, HNSC, and LUSC are the cancer types where LINC01749 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01749 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.062	.010	4	view →
HNSC	Female	All	+0.035	.021	2	view →
LUSC	All	All	+0.021	.023	2	view →
LUAD	All	All	+0.008	.016	2	view →
KIRC	All	All	−0.008	.048	2	view →
CHOL	All	All	+0.076	.010	1	view →
THCA	All	All	−0.005	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC01749–COAD

Open the COAD breakdown →