LINC01740

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01740 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LINC01740 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC01740 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC01740 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, UCS, and PAAD are the cancer types where LINC01740 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSQuartileIV0.8410.486.00344view →
UCSOSMedianAll0.7900.549.00442view →
PAADDFSQuartileAll0.4070.196.00734view →
UVMDFSQuartileIII,IV0.2820.690.00231view →
THCAOSQuartileII,III,IV0.6040.970.00721view →
READOSTertileAll0.7140.951<.00118view →
LIHCDFSTertileAll0.1840.347.00218view →
LAMLDFSQuartileAll0.2250.534.00218view →
BLCAOSTertileIV0.3330.709.00616view →
OVOSTertileIV0.4480.851<.00116view →
ACCOSTertileIII,IV0.2470.657.01115view →
LGGDFSMedianAll0.6820.789.00313view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration