Across TCGA pan-cancer cohorts, LINC01740 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01740’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC01740 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01740 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.
THCA, BRCA, and KIRP are the cancer types where LINC01740 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01740 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.