LINC01727

Across TCGA pan-cancer cohorts, LINC01727 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LINC01727 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC01727 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC01727 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

HNSC, CESC, and LUAD are the cancer types where LINC01727 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.755	0.640	<.001	135	view →
CESC	DFS	Median	All	0.839	0.639	<.001	104	view →
LUAD	DFS	Tertile	All	0.844	0.722	<.001	72	view →
SKCM	OS	Median	All	0.441	0.263	<.001	64	view →
KIRC	DFS	Median	II,III,IV	0.641	0.463	.012	35	view →
COAD	DFS	Quartile	III,IV	0.724	0.518	.008	24	view →
ESCA	DFS	Median	III,IV	0.570	0.309	.001	20	view →
ACC	OS	Quartile	III,IV	0.471	0.901	.008	18	view →
CHOL	DFS	Quartile	All	0.892	0.316	.006	15	view →
LUSC	DFS	Tertile	III,IV	0.684	0.393	.020	14	view →
THCA	OS	Quartile	IV	0.810	0.987	.009	14	view →
OV	OS	Median	IV	0.776	0.514	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LINC01727–HNSC (DFS)

Open the HNSC breakdown →