LINC01687

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01687 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC01687’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01687 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01687 is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.

KIRC, COAD, and READ are the cancer types where LINC01687 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01687 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleII,III,IV−0.462<.00111view →
COADFemaleIII,IV−1.280<.00110view →
READAllAll−0.524<.0017view →
KIRPAllAll−0.381.0014view →
CHOLAllAll−0.867<.0013view →
LUSCAllAll+0.145.0053view →
PRADAllAll+0.539<.0012view →
LUADAllAll+0.132.0082view →
STADAllAll+0.113.0471view →
HNSCMaleAll+0.049.0251view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC01687–KIRC

Tumor-vs-normal expression box plot for LINC01687 RNA in KIRC.

Open the KIRC breakdown →

Exploration