LINC01685

Across TCGA pan-cancer cohorts, LINC01685 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LINC01685 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher LINC01685 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01685 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CHOL show a favorable association.

TGCT, HNSC, and SKCM are the cancer types where LINC01685 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	III,IV	0.501	1.000	.014	54	view →
HNSC	DFS	Tertile	All	0.687	0.282	.003	48	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	27	view →
OV	OS	Tertile	II,III,IV	0.535	0.697	.021	24	view →
MESO	OS	Tertile	IV	0.269	0.639	.027	18	view →
CHOL	DFS	Tertile	All	1.000	0.329	.020	18	view →
THCA	OS	Tertile	II,III,IV	0.882	0.972	.006	18	view →
LIHC	DFS	Tertile	II,III,IV	0.100	0.463	.048	18	view →
KICH	DFS	Tertile	III,IV	0.025	0.773	<.001	18	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
UVM	DFS	Quartile	All	0.879	0.643	.019	9	view →
ESCA	DFS	Tertile	II,III,IV	0.482	0.258	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LINC01685–TGCT (OS)

Open the TGCT breakdown →