LINC01685

Across TCGA pan-cancer cohorts, LINC01685 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01685’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01685 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01685 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and KICH are the cancer types where LINC01685 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01685 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.104	<.001	12	view →
KIRP	All	II,III,IV	−0.150	<.001	11	view →
KICH	Female	All	−0.169	.003	4	view →
LUSC	Male	II,III,IV	−0.032	.046	2	view →
COAD	Female	All	−0.029	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC01685–KIRC

Open the KIRC breakdown →