LINC01681

Across TCGA pan-cancer cohorts, LINC01681 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated LINC01681 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC01681 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01681 expression acts as an unfavorable survival marker, although some lineages such as ACC and MESO show a favorable association.

KIRC, KIRP, and ACC are the cancer types where LINC01681 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.741	0.818	.002	78	view →
KIRP	DFS	Tertile	III,IV	0.167	0.725	<.001	51	view →
ACC	OS	Median	II,III,IV	0.967	0.745	.002	48	view →
THCA	OS	Tertile	All	0.766	0.958	<.001	48	view →
LUAD	DFS	Tertile	IV	0.376	0.810	<.001	36	view →
LGG	OS	Tertile	All	0.629	0.827	<.001	27	view →
ESCA	DFS	Quartile	II,III,IV	0.362	0.564	.003	19	view →
COAD	DFS	Tertile	IV	0.159	0.503	.006	18	view →
MESO	DFS	Tertile	IV	0.623	0.202	.002	15	view →
READ	OS	Tertile	All	0.294	0.753	.028	12	view →
HNSC	DFS	Tertile	IV	0.735	0.605	.016	7	view →
BRCA	OS	Quartile	All	0.894	0.935	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

LINC01681–KIRC (OS)

Open the KIRC breakdown →