LINC01681

Across TCGA pan-cancer cohorts, LINC01681 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC01681’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01681 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01681 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

LUAD, LIHC, and LUSC are the cancer types where LINC01681 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01681 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.090	.001	4	view →
LIHC	Male	All	+0.815	<.001	2	view →
LUSC	Male	All	+0.086	.021	2	view →
HNSC	All	All	+0.185	.039	1	view →
KIRP	Female	All	−0.052	.012	1	view →
KIRC	Female	All	−0.028	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LINC01681–LUAD

Open the LUAD breakdown →