LINC01607

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01607 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC01607’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01607 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01607 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and LUAD are the cancer types where LINC01607 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01607 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleII,III,IV−0.803<.00110view →
THCAMaleIII,IV−1.372<.0019view →
LUADFemaleIII,IV+1.387<.0018view →
LIHCMaleAll+0.656<.0018view →
HNSCMaleIV+0.774.0057view →
LUSCFemaleAll+1.411<.0016view →
UCECAllAll+1.068<.0016view →
KICHAllII,III,IV+0.835.0163view →
STADAllAll+0.270.0043view →
COADAllAll+0.249.0043view →
CHOLAllAll+1.191.0092view →
PRADAllAll+0.437<.0012view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC01607–KIRC

Tumor-vs-normal expression box plot for LINC01607 RNA in KIRC.

Open the KIRC breakdown →

Exploration