LINC01587

Across TCGA patient cohorts, LINC01587 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01587-associated genes across cancer lineages are UBTFL3, RNU6-468P, and MIR5708. Each is linked with LINC01587 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01587-to-partner and partner-to-LINC01587 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBTFL3 grouped by LINC01587-low versus LINC01587-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01587→partner) and Y-score (partner→LINC01587) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBTFL3 →	+0.079	+7.954	<.001	.008	3	1
STAD	RNU6-468P →	+0.346	+4.520	.001	.005	3	1
HNSC	MIR5708 →	+0.268	+7.954	<.001	.008	3	1
COAD	RNU105C →	+0.427	+7.741	<.001	.009	3	1
UCEC	RNU6-598P →	+0.578	+5.242	<.001	.007	3	1
UCEC	RNU6-34P →	+0.642	+7.470	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

UBTFL3 by LINC01587 expression — HNSC

Explore this box plot interactively →