LINC01580

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01580 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC01580 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC01580 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01580 expression acts as an unfavorable survival marker, although some lineages such as OV and LIHC show a favorable association.

KIRC, COAD, and UCEC are the cancer types where LINC01580 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSTertileII,III,IV0.4460.742<.001144view →
COADOSTertileAll0.2450.645<.001117view →
UCECOSTertileAll0.4100.697<.001102view →
KICHOSTertileAll0.0820.877<.00151view →
UVMDFSTertileAll0.2590.750.01436view →
DLBCDFSTertileIV0.1200.683.00136view →
LUADDFSTertileIV0.3420.893<.00136view →
READOSTertileIV0.1110.893<.00127view →
PCPGDFSTertileAll0.1630.832<.00118view →
LUSCDFSTertileIII,IV0.3550.789<.00118view →
LAMLDFSQuartileAll0.4240.616.01516view →
LGGDFSQuartileAll0.7360.857<.00116view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LINC01580–KIRC (OS)

Kaplan–Meier survival curve for LINC01580 RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration