LINC01580

Across TCGA pan-cancer cohorts, LINC01580 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01580’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01580 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01580 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

HNSC and LIHC are the cancer types where LINC01580 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01580 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	−0.025	.030	3	view →
LIHC	All	All	+0.074	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LINC01580–HNSC

Open the HNSC breakdown →