Across TCGA pan-cancer cohorts, LINC01568 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01568’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01568 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01568 is over-expressed in tumor, although a few such as KIRC and PAAD show the opposite, repressed pattern.
KIRC, PAAD, and HNSC are the cancer types where LINC01568 tumor–normal differential expression is most reproducible.