LINC01553

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC01553 mutation is significantly associated with the RNA expression of many other genes, with 228 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01553-associated genes across cancer lineages are RNU1-62P, SETP4, and IGLVI-38. Each is linked with LINC01553 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01553-to-partner and partner-to-LINC01553 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-62P grouped by LINC01553-low versus LINC01553-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01553→partner) and Y-score (partner→LINC01553) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU1-62P →+0.228+4.539<.001.00832
UCECSETP4 →+0.157+3.193<.001<.00132
UCECIGLVI-38 →+0.099+2.883.008.00132
COADOR5D3P →+0.046+4.595.004.00432
COADPIGPP3 →+0.218+3.602<.001.00532
COADSLC20A1P3 →+0.051+4.595.009.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 228 associations by consensus.

RNU1-62P by LINC01553 expression — CESC

Box plot of RNU1-62P in LINC01553-low vs LINC01553-high samples in CESC.

Explore this box plot interactively →

Exploration