LINC01553

Across TCGA patient cohorts, LINC01553 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01553-associated genes across cancer lineages are EGFR_pY1068, JNK_pT183_Y185, and MYH11. Each is linked with LINC01553 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01553-to-partner and partner-to-LINC01553 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by LINC01553-low versus LINC01553-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01553→partner) and Y-score (partner→LINC01553) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.257	-2.321	.041	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.194	-2.999	.021	.035	3	1
UCEC	MYH11 →	+1.261	+2.321	.028	.035	2	1
UCEC	PEA-15 →	+0.242	+3.459	.010	.005	2	1
UCEC	Tuberin →	+0.393	+3.009	.003	.019	2	1
UCEC	YAP →	+0.151	+2.321	.045	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

EGFR_pY1068 by LINC01553 expression — UCEC

Explore this box plot interactively →