LINC01541

Across TCGA pan-cancer cohorts, LINC01541 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LINC01541 data layer.

The strongest signal is observed in thymoma (THYM), where higher LINC01541 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01541 expression acts as an unfavorable survival marker, although some lineages such as LUSC and UCEC show a favorable association.

THYM, LUAD, and GBM are the cancer types where LINC01541 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	III,IV	0.229	1.000	<.001	48	view →
LUAD	OS	Tertile	II,III,IV	0.305	0.598	.015	42	view →
GBM	DFS	Tertile	All	0.099	0.268	<.001	36	view →
ESCA	DFS	Tertile	All	0.146	0.748	.001	18	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
LGG	DFS	Tertile	All	0.699	0.841	.007	18	view →
LIHC	OS	Tertile	III,IV	0.329	0.647	.001	18	view →
SARC	OS	Tertile	All	0.200	0.526	.005	18	view →
CHOL	DFS	Tertile	II,III,IV	0.139	0.439	.024	15	view →
KIRC	DFS	Tertile	III,IV	0.569	0.776	.032	12	view →
LUSC	OS	Tertile	All	0.864	0.763	.035	12	view →
UCEC	DFS	Tertile	All	0.942	0.866	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LINC01541–THYM (OS)

Open the THYM breakdown →