LINC01541

Across TCGA pan-cancer cohorts, LINC01541 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01541’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01541 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01541 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

KIRC, BRCA, and THCA are the cancer types where LINC01541 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01541 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.082	<.001	11	view →
BRCA	All	IV	−0.075	.004	4	view →
THCA	All	All	−0.005	.003	3	view →
UCEC	All	All	+1.371	.036	2	view →
KIRP	All	All	−0.097	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC01541–KIRC

Open the KIRC breakdown →