Q-omics provides the consensus-scored LINC01539 profile across patient tissues and cancer cell-line models. LINC01539 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, LINC01539 is differentially expressed in 6, with the highest sampling consensus in THCA. Additionally, LINC01539 RNA expression shows 10,115 significant protein co-abundance associations, with the highest sampling consensus in HNSC. Together, these results highlight UVM, THCA, and HNSC as cancer lineages where LINC01539 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01539 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01539 survival associations across molecular data types. LINC01539 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01539 RNA expression–survival associations across cancer types. High LINC01539 expression shows unfavorable associations in UVM, LAML and KICH, but favorable associations in ESCA, HNSC and STAD. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .007). Together, the overview and detailed table identify UVM as the clearest survival context for LINC01539 RNA expression.
This table summarizes LINC01539 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01539. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01539 shows lower tumor expression in THCA, KIRP, COAD, KICH and UCEC and higher tumor expression in LUSC. The THCA box plot shows higher LINC01539 RNA expression in normal versus tumor tissue (log2 FC = −1.584, t-test p < 0.001).
This table shows molecular features associated with LINC01539 in patient tissues and cancer cell lines. In patient samples, LINC01539 shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set.
