Across TCGA pan-cancer cohorts, LINC01527 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01527’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01527 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01527 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

LUSC, BRCA, and HNSC are the cancer types where LINC01527 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01527 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.858	<.001	6	view →
BRCA	All	II,III,IV	+0.025	.048	2	view →
HNSC	All	All	+0.657	.042	1	view →
STAD	All	II,III,IV	−0.260	.049	1	view →
BLCA	All	IV	+0.234	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: LINC01527 RNA expression & survival · all LINC01527 data types