Q-omics provides the consensus-scored LINC01527 profile across patient tissues and cancer cell-line models. LINC01527 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LINC01527 is differentially expressed in 5, with the highest sampling consensus in LUSC. Additionally, LINC01527 RNA expression shows 9,192 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight KIRC, LUSC, and ESCA as cancer lineages where LINC01527 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01527 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01527 survival associations across molecular data types. LINC01527 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01527 RNA expression–survival associations across cancer types. High LINC01527 expression shows unfavorable associations in KIRC, READ, UCEC and SKCM, but favorable associations in CESC and LGG. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LINC01527 RNA expression.
This table summarizes LINC01527 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01527. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01527 shows lower tumor expression in STAD and higher tumor expression in LUSC, BRCA, HNSC and BLCA. The LUSC box plot shows higher LINC01527 RNA expression in tumor versus normal tissue (log2 FC = +0.858, t-test p < 0.001).
This table shows molecular features associated with LINC01527 in patient tissues and cancer cell lines. In patient samples, LINC01527 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
