LINC01516

Across TCGA patient cohorts, LINC01516 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC01516-associated GO terms across cancer lineages are Cellular response to growth hormone stimulus, Regulation of protein serine/threonine kinase activity, and Negative regulation of protein serine/threonine kinase activity. Each is linked with LINC01516 in more than 13 cancer types. Because this analysis shows association rather than direction, both LINC01516-to-partner and partner-to-LINC01516 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to growth hormone stimulus grouped by LINC01516-low versus LINC01516-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01516→partner) and Y-score (partner→LINC01516) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cellular response to growth hormone stimulus →	+0.104	+0.227	<.001	<.001	3	12
KIRC	Regulation of protein serine/threonine kinase activity →	+0.023	+0.049	<.001	.002	3	12
ESCA	Negative regulation of protein serine/threonine kinase activity →	+0.061	+0.106	.001	.007	1	14
ESCA	ER-nucleus signaling pathway →	+0.086	+0.143	<.001	<.001	3	12
LAML	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.026	+0.024	<.001	.002	2	12
ESCA	Regulation of small GTPase mediated signal transduction →	+0.040	+0.120	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,747 associations by consensus.

Cellular response to growth hormone stimulus by LINC01516 expression — ESCA

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