LINC01516

Across TCGA pan-cancer cohorts, LINC01516 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LINC01516 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher LINC01516 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC01516 expression acts as an unfavorable survival marker, although some lineages such as LGG and BLCA show a favorable association.

LGG, KIRP, and HNSC are the cancer types where LINC01516 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Quartile	All	0.504	0.278	<.001	33	view →
KIRP	DFS	Tertile	IV	0.039	0.526	.016	30	view →
HNSC	OS	Quartile	III,IV	0.513	0.676	.004	25	view →
THYM	DFS	Quartile	All	0.649	0.951	.002	20	view →
BLCA	OS	Tertile	III,IV	0.626	0.371	.017	17	view →
KIRC	OS	Tertile	All	0.566	0.682	.025	13	view →
ESCA	OS	Median	II,III,IV	0.618	0.782	.009	10	view →
SKCM	OS	Median	IV	0.671	0.160	.028	10	view →
COAD	OS	Median	IV	0.849	0.287	.003	9	view →
READ	DFS	Tertile	IV	0.179	0.936	.010	7	view →
BRCA	OS	Tertile	II,III,IV	0.938	0.962	.025	5	view →
UCEC	DFS	Tertile	IV	0.476	0.780	.026	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LINC01516–LGG (DFS)

Open the LGG breakdown →