Across TCGA pan-cancer cohorts, LINC01490 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01490’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where LINC01490 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01490 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
KICH and THCA are the cancer types where LINC01490 tumor–normal differential expression is most reproducible.